What is so important about clinical studies?

As you make a decision about which product to choose, clinical studies are one of the most important sources of information. Many companies including ours emphasize clinical studies and use this to provide you key information. However...

Not all studies are same. True clinical studies are done in controlled settings and reported as 'posters' at scientific meetings and in journals dedicated in our case to either Obstetrics & Gynecology or by specialists in Reproductive Medicine. Studies presented this way must be “peer reviewed” by other specialists before they can be published. That's the way that medical professionals know they can trust the research.

As you consider other methods and products; take the time to check out the clinical studies that they quote. Some products don't provide any scientific backing, some talk about studies which are not reviewed by specialists, some are not published in specialist journals, and some don't provide you with useful information about how they can help you get pregnant.

Trust our science

The papers below show that our products have true clinical backing, with a wide range of posters and papers published over a number of years, and all of them reviewed by specialists. Crucially these papers show how they provide really useful information that puts you in control of your fertility journey:

The accuracy of ovulation confirmation by OvuSense is based on the data set originally published at the 2013 ASRM meeting as a quality index: Papaioannou S, Aslam M (2013) , and developed in the key publication outlining the accuracy and positive predictive value of advance prediction of ovulation shown at the 2014 ESHRE meeting: Papaioannou S, Delkos D, Pardey J (2014).

The comfort and ease of use of the OvuCore sensor were published in the Journal of Obstetrics and Gynecology in 2013, and this survey is repeated annually with our customers with continuous as good or better results: Papaioannou S, Aslam M (2013).

Further publications have identified:

- the wide spread of day of ovulation in OvuSense user cycles:
Hurst BS, Citron C (2020) Normalised Ovulation Timing in Population using Core Body Temperature Monitoring to conceive S-194 Society for Reproductive Investigation, 2020 Annual Meeting.

- the association of atypical cycle patterns displayed by the OvuSense Pro product and ovulatory issues:
Karoshi M, Hurst B (2020) Atypical Temperature Patterns as an Aid to Identify Infertility Issues and Miscarriage Risk. P-628 European Society of Human Reproduction and Embryology 36th Annual Meeting.

- the atypical cycle patterns which led to the development of the OvuSense Pro product:
Hurst BS, Karoshi M (2020) Atypical Core Body Temperature patterns and the wider implications for conditions related to pregnancy, infertility, and miscarriage risk P-833 American Society for Reproductive Medicine 76th Annual conference. Poster; Fertility and Sterility - September 2020 Volume 114, Issue 3, Supplement, Pages e446–e447 |
Hurst BS, Pirrie A (2019) Atypical vaginal temperature patterns may identify subtle not yet recognised causes of infertility P-345 American Society for Reproductive Medicine 75th Annual conference.;, Fertility and Sterility - September 2019 Volume 112, Issue 3, Supplement, Pages e244–e245;

The clinical proof for OvuFirst is provided by a Fertility Focus side by side study of OvuFirst with the OvuCore vaginal temperature sensor (2021), documented as a class II medical device in the notified body reviewed CE Certificate Technical File.

The background science for our products is provided in the following publications:
Papaioannou S, Aslam M (2012) Ovulation assessment by vaginal temperature analysis (Ovusense Fertility Monitoring System) in comparison to oral temperature recording. American Society for Reproductive Medicine 68th Annual conference.; Papaioannou S, Aslam M (2012) Ovulation Assessment and Fertile Period Prediction by Portable Computerised Vaginal Temperature Analysis – The OvuSense Advanced Fertility Monitoring System. European Society of Human Reproduction and Embryology 28th Annual Conference.

Our products are backed by a significant number of patents. Very few other products have this degree of proof of novel technology:

US Patents: US8684944, US8496597, US9155522, US9155523, US20190110692; European patents: EP1485690, EP2061380, DE20 2014 011 334, DE20 2014 011 335; Chinese patent: CN1650154

Which fertility monitor is right for me?

Compare OvuSense with other methods for monitoring your ovulation and reproductive cycle.

As you consider which fertility monitor fits you best some typical things to consider are:

  1. How large a fertile window will it detect so you can maximize the time when you're trying to conceive
  2. How accurate is it at confirming ovulation - the less accurate the less chance of it helping you in your next cycle
  3. Can it predict ovulation using the current cycle data - something we like to call realtime prediction
  4. Does the system work for PCOS and irregular cycles
  5. Can it help your doctor screen for fertility issues
  6. Can it help you and your doctor monitor your medication or treatment

Each of the statistics quoted below are derived from clinical evidence available on fertility monitoring methods and products. Pro refers to the OvuSense Pro clinician portal. Click on the 'i' icon next to each method in the table, or directly on the method in the table on mobile devices to find out more about the clinical evidence.

  Feature/ How many does it get right
Fertile window prediction days
Confirms ovulation
Live ovulation prediction
PCOS and irregular cycles
Screen for fertility issues
Track medications and treatments
(Skin-Worn Temperature)
OF 8 days 8 days 90% 90%
OvuSense OvuCore
(Core Body Temperature)
OS Core 8 days 8 days 99% 99% 96% 96%   Pro Pro
Fertility Tracker Apps
FTA 4-6 days 4-6 days 21% 21%
Basal Body Temperature
BBT 6 days 6 days 78% 78%
Skin Worn/
Fertility Bracelet Devices
SW/ FB 6 days 6 days 78% 78%
Ovulation Predictor
Kits and Monitors
OPK/ OPM 4-6 days 4-6 days 92% 92%
Serum Progesterone
SP 4-6 days 4-6 days 100% 100%
US 6 days 6 days 100% 100% 100% 100%

Fertility Testing Methods Key

  • OF OvuFirst (Skin Temperature)
  • OS Core OvuSense OvuCore (Core Body Temperature)
  • BBT Basal Body Temperature
  • FTA Fertility Tracker Apps
  • SWD Skin Worn Devices
  • FBD Fertility Bracelet Devices
  • OPK Ovulation Predictor Kits (urine strips)
  • OPM Ovulation Prediction Monitors (urine strips)
  • SP Serum Progesterone
  • US Ultrasound